Rheumatoid Arthritis Medications for Aging Adults
Rheumatoid arthritis (RA) can be especially challenging for aging adults, causing joint pain, stiffness, and reduced mobility.
Early and effective treatment is crucial to manage symptoms and prevent further joint damage.
Fortunately, a variety of medications are available today to help seniors maintain a better quality of life while living with RA.
Here’s a look at common rheumatoid arthritis medications often recommended for aging adults:
Understanding Treatment Options for Better Joint Health

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Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
NSAIDs like ibuprofen and naproxen help relieve pain and reduce inflammation.
While effective, long-term use requires careful monitoring due to potential side effects such as gastrointestinal bleeding or cardiovascular issues, especially in older adults. -
Corticosteroids
Medications like prednisone are powerful anti-inflammatories that can quickly control RA flare-ups.
Doctors typically use corticosteroids for short-term relief due to risks such as osteoporosis and high blood pressure with prolonged use. -
Conventional DMARDs (Disease-Modifying Antirheumatic Drugs)
Drugs like methotrexate, sulfasalazine, and hydroxychloroquine slow the progression of RA by modifying the immune system’s response.
Regular monitoring is needed to manage possible side effects like liver toxicity or lung issues. -
Biologic DMARDs
Biologics such as etanercept (Enbrel) and adalimumab (Humira) target specific parts of the immune system.
These advanced therapies can be highly effective but may increase infection risk, requiring careful evaluation by a healthcare provider. -
JAK Inhibitors
Newer oral medications like tofacitinib (Xeljanz) and baricitinib (Olumiant) offer an alternative to injectable biologics.
They block certain enzymes involved in the inflammatory process but also carry risks of infection and blood clots. -
Pain Management Medications
In addition to RA-specific drugs, doctors may prescribe low-dose antidepressants, nerve pain medications, or topical creams to help manage chronic joint pain and improve comfort levels for aging adults.